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Grade: D

What is Orexis?
Orexis is a non-prescription male enhancement supplement that works by boosting the libido shortly before intercourse to prevent erectile dysfunction (ED), or an inability to maintain an erection.  Like other supplements, Orexis provides erectile support by increasing blood flow to the penis, which helps it stay fuller and more rigid when stimulated.  This also causes an indirect benefit--increased stamina during sexual intercourse.  To enable it to work, Orexis recommend using their supplement 45 minutes before beginning sexual stimulation to promote penis rigidity and fullness.

Ingredients: Orexis contains a proprietary blend of horny goat weed, yohimbe extract, tribulus and other ingredients, which they aren't willing to reveal on their website.

Does it Work?: There is some evidence it may work.  According to a report in the Journal of Urology, horny goat weed was shown to induce erections in rats, improving their copulatory performance.  Other evidence also suggests it contains a compound chemically similar to sildenafil, the active ingredient in Viagra.  Some researchers suggest it may be a viable alternative to Viagra, although it hasn't been approved for this use by the United States Food and Drug Administration (FDA).

Yohimbe has also been shown to improve erectile function, although its reported effects are derived from anecdotal, not scientific, evidence.  There is scientific evidence that it helps improve the libido, especially when combined with ginseng or l-arginine.  But this comes at a huge risk--yohimbe is know to worsen anxiety conditions, and can trigger panic attacks and hallucinations.

Is it Safe?: No.  Yohimbe extract can worsen anxiety conditions, such as generalized anxiety disorder (GAD) or social anxiety disorder (SAD).  It can also cause hallucinations, panic attacks, flushing of the skin, dizziness, an increase in heart rate, high blood pressure and insomnia.  People with heart, blood or psychiatric problems should avoid taking supplements containing yohimbe extract.

Grade: D.  Orexis may reduce ED by improving erectile function, but this comes at an increased risk—some of its ingredients worsen anxiety and heart-related problems, such as rapid heart rate and panic attacks.  If you have a history of heart, blood or psychiatric disorders, this is not an ideal supplement for you.

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